Keyword : "modelling" » 1 result
Equipe 2 » Aim 1 : Natives MSC and stemness
Mesenchymal stromal cells, hypoxia, plasticity, 3d culture, modelling, transcriptome, niche, metabolism, bone marrow, adipose tissue, heterogeneity, mesenchymal stem cells
Presentation :
The main tissues of mesenchymal stem / stromal cells (MSCs) are bone marrow (BM) and adipose tissue (AT). These cells together form a network of cells ranging from the stem cell to the progenitors to the differentiated cells that are osteoblasts, chondrocytes, perivascular cells and medullary adipocytes for bone marrow, CSMs and adipocytes, perivascular cells and fibroblasts for TA MSCs. In humans, the identities and microenvironments of stem cells and progenitors remain to be discovered.
Scientific objective :
The objectives of the group are therefore to characterize these subpopulations of CSM within the MO or TA in adult...