Stromalab - Targeting the stroma to regenerate Médecine régénératrice, thérapie cellulaire, cellules souches mésenchymateuses, tissu adipeux, moelle osseuse, réparation, régénération Regenerative medicine, cell therapy, mesenchymal stem cells, adipose tissue, bone marrow, repair, regeneration

Keyword : "metabolism" » 6 results

Publications » Cholecystokinin is involved in triglyceride fatty acid uptake by rat adipose tissue.

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Plaza A, Merino B, Cano V, Domínguez G, Pérez-Castells J, Soledad Fernández-Alfonso M, Sengenès C, Chowen JA, Ruiz-Gayo M. Journal of Endocrinology  


Publications » Immuno-metabolism and adipose tissue: The key role of hematopoietic stem cells.

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Cousin B, Casteilla L, Laharrague P, Luche E, Lorsignol A, Cuminetti V, Paupert J. Biochimie.


Equipe 2 » Aim 1 : Natives MSC and stemness

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Presentation : The main tissues of mesenchymal stem / stromal cells (MSCs) are bone marrow (BM) and adipose tissue (AT). These cells together form a network of cells ranging from the stem cell to the progenitors to the differentiated cells that are osteoblasts, chondrocytes, perivascular cells and medullary adipocytes for bone marrow,  CSMs and adipocytes, perivascular cells and fibroblasts for TA MSCs. In humans, the identities and microenvironments of stem cells and progenitors remain to be discovered.   Scientific objective : The objectives of the group are therefore to characterize these subpopulations of CSM within the MO or TA in adult...


Publications » Lactate induces FGF21 expression in adipocytes through a p38-MAPK pathway.

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Jeanson Y, Ribas F, Galinier A, Arnaud E, Ducos M, André M, Chenouard V, Villarroya F, Casteilla L, Carrière A. Biochem J.


Équipe 1 » Aim 1 : Repair / Regeneration and ASC biology

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Presentation : The objective of our sub-theme is to contribute to the understanding of the mechanisms that inhibit regeneration in adult mammals.   Scientific Objectives : The objective is to identify, using adipose tissue as a model, the signals from the stroma and in particular from mesenchymal stromal cells (ASC), which may induce regeneration of tissues and/or organs and to determine how these cells could participate in regeneration. Particular attention is paid to the study of the cellular dynamics of adipose tissue and the involvement of metabolism in these processes.   Expected Health Outcomes : From a therapeutic point of view,...


Publications » A New Role for Browning as a Redox and Stress Adaptive Mechanism?

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Jeanson Y, Carrière A, Casteilla L. Front Endocrinol