Stromalab - Targeting the stroma to regenerate Médecine régénératrice, thérapie cellulaire, cellules souches mésenchymateuses, tissu adipeux, moelle osseuse, réparation, régénération Regenerative medicine, cell therapy, mesenchymal stem cells, adipose tissue, bone marrow, repair, regeneration

Keyword : "clinical trial" » 5 results

Publications » Spatial and temporal structure of the clinical research based on mesenchymal stromal cells: A network analysis.

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Monsarrat P, Kemoun P, Vergnes JN, Sensebe L, Casteilla L, Planat-Benard V. Cytotherapy


Equipe 2 » Aim2 : Interaction MSC/Immunity

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Introduction :   Mesenchymal stromal cells, due to their immunoregulatory properties, are used in many clinical trials to treat different disorders such as dysimmune and inflammatory diseases, hematopoietic stem cell transplantation and organ transplants. These immunosuppressive capacities of MSCs play a central role during tissue repair. Indeed, MSCs are sensors of the inflammatory environment, and therefore can modify macrophage functions (in particular MSCs can "switch" M1-pro-inflammatory macrophages in M2-anti-inflammatory macrophages). However, the interaction between MФ and MSCs and its effect on the MSC properties are poorly understood. Moreover, for a better use of these cells in clinic, we need to determine...


Publications » Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial.

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Pers YM, Rackwitz L, Ferreira R, Pullig O, Delfour C, Barry F, Sensebe L, Casteilla L, Fleury S, Bourin P, Noël D, Canovas F, Cyteval C, Lisignoli G, Schrauth J, Haddad D, Domergue S, Noeth U, Jorgensen C; ADIPOA Consortium. Stem Cells Transl Med


Publications » An Innovative, Comprehensive Mapping and Multiscale Analysis of Registered Trials for Stem Cell-Based Regenerative Medicine

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Monsarrat P, Vergnes JN, Planat-Bénard V, Ravaud P, Kémoun P, Sensebé L, Casteilla L. Stem Cells Transl Med.


Publications » A relativity concept in mesenchymal stromal cell manufacturing

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Martin I, De Boer J, Sensebe L; MSC Committee of the International Society for Cellular Therapy. Cytotherapy