Stromalab - Targeting the stroma to regenerate Médecine régénératrice, thérapie cellulaire, cellules souches mésenchymateuses, tissu adipeux, moelle osseuse, réparation, régénération Regenerative medicine, cell therapy, mesenchymal stem cells, adipose tissue, bone marrow, repair, regeneration

E Cell France – Potency test for therapeutic cell

ECellFrance ( is a national network for adult’s MSC-based therapy development. ECellFrance offers to assist both academic and industrial partners with the implementation of their pre-clinical and/or clinical programs in the emerging field of cell-based therapies. The ECellFrance network for regenerative medecine provides services covering the entire MSC-based production and development pipeline:

  • MSC production
  • Safety and potency tests for MSC
  • Immunomonitoring of MSC-treated patients
  • Pre-clinical development of MSC-based medicinal products
  • Regulatory support services
  • Clinical trial support services for phase I and phase II trials


Scientific Aim:

Currently, adult MSCs are increasingly used in clinical trial. Production, development and use of MSC-based medical products require safety and potency test. Toulouse platform STROMALab is intended to provide new quality control test in order to improve MSCs-production safety but also new potency assay in order to evaluate MSCs functional ability before therapeutic administration.


STROMALab Involvement:

STROMALab laboratory is involved in ECellFrance national network at different levels:

  • It provides its MSCs and ASCs (adipose tissue derived mesenchymal stem cell) expertise. This team is involved in the field of :
  • Safety and potency test standardization of MSC/ASC based-medicinal products.
  • Genetic stability of CSM/ASC.
  • Regenerative and immunomodulatory property of MSC and ASC.
  • Ischemic diseases
  • In collaboration with EFS, it provide expertise for the national network in:
  • GMP production of Advanced Therapy Medicinal Products (ATMP) in accordance with regulation in EFS production platform (Toulouse, Créteil, Grenoble and Besançon).
  • Manufacturing processes development.
  • Drafting of Investigational Medicinal Product Dossier (IMPD) for clinical trial.

Both team’s managers are involved in steering and scientific advisory board.

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Sophie Dupuis-Coronas


+33 5 34 60 95 18


  • BD LSR Fortessa Cell Analyzer, 5 lasers which enables the detection of up to 18 colors simultaneously.
  • BD Canto II Cell Analyzer, 8 colors.
  • BD FACSAria Fusion Cell Sorter, 4 lasers.
  • Perkin Elmer Operetta High Content Screening Systems.
  • Amnis ImageStreamX Mark II Imaging Flow Cytometer.