A post-doc position is now opened in STROMALab Institute, Toulouse, France, in the team “Adipose Tissue Plasticity”, aiming at studying the cellular dynamics in tissue repair/regeneration in adult mammals in vivo.
Academic context: This position funded by ANR is part of collaboration between two research groups: “Adipose Tissue Hematopoiesis and Tissue Integrity”, led by Beatrice Cousin within STROMALab in Toulouse (www.stromalab.com) and “Regenerative Therapies For Cardiac And Vascular Diseases” led by Jean-Sebastien Silvestre in Paris Cardiovascular Research Center (http://silvestrelab.weebly.com/).
Scientific context: Emerging evidences suggest that myeloid-derived cells may provide the necessary signals to drive tissue remodeling after injury. The classical paradigm indicates that these cells mainly derive from genuine hematopoietic progenitors residing in the bone marrow. However, we published several original reports showing that in addition to the bone marrow, adipose tissue constitutes an alternative source of innate immune cells that may contribute to inter-organ dialogue, and participate to tissue homeostasis and repair/regeneration processes (Poglio et al., Stem Cell, 2010; Blood 2012; Luche et al. J Cell Physiol, 2015; Ngkelo et al., J Exp Med. 2016; Luche et al., in revision).